Varaico: Literature-Extracted Genetic Variants

LRRC3B

29 papers

RefSeq Summary

The protein encoded by this gene is a tumor suppressor, with lowered expression levels found in gastric, renal, colorectal, lung, and breast cancer tissues. The promoter of this gene is frequently hyp...

Pfam Domains

LRRNTaa 33–63UCSCLeucine rich repeat N-terminal domain

LRR_8aa 64–114UCSCLeucine rich repeat

LRR_1aa 114–136UCSCLeucine Rich Repeat

Gene Aliases

HGNC Name

leucine rich repeat containing 3B

HGNC Alias Symbol

LRP15

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_052953.4

p.V225L

c.673G>C

Surrounding Variants

1 paper

NM_052953.4

p.V225L

c.673G>T

1 paper

NM_052953.4

p.E230V

c.689A>T

1 paper

NM_052953.4

p.F214L

c.642C>A

1 paper

NM_052953.4

p.F214L

c.642C>G

1 paper

NM_052953.4

p.F214L

c.640T>C

1 paper

NM_052953.4

p.K247N

c.741G>C

1 paper

NM_052953.4

p.K247N

c.741G>T

2 papers

NM_052953.4

p.K199fs

c.595_596fs

1 paper

NM_052953.4

p.P198Fs

c.594delinsTAFs

2 papers

NM_052953.4

p.K199delFs

c.595delA

1 paper

NM_052953.4

p.D254N

c.760G>A

1 paper

NM_052953.4

p.D191D

c.573C>T