Varaico: Literature-Extracted Genetic Variants

LRRFIP2

49 papers

RefSeq Summary

The protein encoded by this gene, along with MYD88, binds to the cytosolic tail of toll-like receptor 4 (TLR4), which results in activation of nuclear factor kappa B signaling. The ubiquitin-like prot...

Pfam Domains

LRRFIPaa 31–145UCSCLRRFIP family

LRRFIPaa 279–480UCSCLRRFIP family

Gene Aliases

HGNC Name

LRR binding FLII interacting protein 2

HGNC Alias Symbol

HUFI-2

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_006309.4

p.H130delFs

c.388_389delTG

Surrounding Variants

1 paper

NM_006309.4

p.S118L

c.353C>T

2 papers

NM_006309.4

p.Y184C

c.551A>G

1 paper

NM_006309.4

p.L197P

c.590T>C

1 paper

NM_006309.4

p.R218Q

c.653G>A

1 paper

NM_006309.4

p.I230delFs

c.688delT

1 paper

NM_006309.4

p.R234*

c.700C>T

1 paper

NM_006309.4

p.H90R

c.269A>G

1 paper

NM_006309.4

p.R270H

c.809G>A