Varaico: Literature-Extracted Genetic Variants

LRRFIP2

49 papers

RefSeq Summary

The protein encoded by this gene, along with MYD88, binds to the cytosolic tail of toll-like receptor 4 (TLR4), which results in activation of nuclear factor kappa B signaling. The ubiquitin-like prot...

Pfam Domains

LRRFIPaa 31–145UCSCLRRFIP family

LRRFIPaa 279–480UCSCLRRFIP family

Gene Aliases

HGNC Name

LRR binding FLII interacting protein 2

HGNC Alias Symbol

HUFI-2

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_006309.4

p.R39W

c.115C>T

Surrounding Variants

1 paper

NM_006309.4

p.R42L

c.125G>T

1 paper

NM_006309.4

p.R46R

c.136A>C

1 paper

NM_006309.4

p.R46I

c.137G>T

1 paper

NM_006309.4

p.I48T

c.143T>C

1 paper

NM_006309.4

p.M50R

c.149T>G

1 paper

NM_006309.4

p.E59fs

c.175_176fs

1 paper

NM_006309.4

p.R67Q

c.200G>A

1 paper

NM_006309.4

p.L76_E77Splc

c.228+150C>T

1 paper

NM_006309.4

p.H90R

c.269A>G