Varaico: Literature-Extracted Genetic Variants

LRRN2

69 papers

RefSeq Summary

The protein encoded by this gene belongs to the leucine-rich repeat superfamily. This gene was found to be amplified and overexpressed in malignant gliomas. The encoded protein has homology with other...

Pfam Domains

LRR_8aa 93–153UCSCLeucine rich repeat

LRR_8aa 213–273UCSCLeucine rich repeat

LRR_8aa 310–371UCSCLeucine rich repeat

I-setaa 427–514UCSCImmunoglobulin I-set domain

Gene Aliases

HGNC Name

leucine rich repeat neuronal 2

HGNC Previous Symbol

LRRN5

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_201630.2

p.V659A

c.1976T>C

Surrounding Variants

1 paper

NM_201630.2

p.G653D

c.1958G>A

1 paper

NM_201630.2

p.G653R

c.1957G>C

1 paper

NM_201630.2

p.A644S

c.1930G>T

1 paper

NM_201630.2

p.A638V

c.1913C>T

1 paper

NM_201630.2

p.P689H

c.2066C>A

4 papers

NM_201630.2

p.P692S

c.2074C>T

1 paper

NM_201630.2

p.P707L

c.2120C>T

1 paper

NM_201630.2

p.D603Y

c.1807G>T

1 paper

NM_201630.2

p.T591T

c.1773G>A

1 paper

NM_201630.2

p.R574H

c.1721G>A

1 paper

NM_201630.2

p.T551I

c.1652C>T

1 paper

NM_201630.2

p.P549H

c.1646C>A