Varaico: Literature-Extracted Genetic Variants

LRRN2

69 papers

RefSeq Summary

The protein encoded by this gene belongs to the leucine-rich repeat superfamily. This gene was found to be amplified and overexpressed in malignant gliomas. The encoded protein has homology with other...

Pfam Domains

LRR_8aa 93–153UCSCLeucine rich repeat

LRR_8aa 213–273UCSCLeucine rich repeat

LRR_8aa 310–371UCSCLeucine rich repeat

I-setaa 427–514UCSCImmunoglobulin I-set domain

Gene Aliases

HGNC Name

leucine rich repeat neuronal 2

HGNC Previous Symbol

LRRN5

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

5 papers

NM_201630.2

p.L518V

c.1552C>G

Surrounding Variants

1 paper

NM_201630.2

p.L519H

c.1556T>A

1 paper

NM_201630.2

p.E525K

c.1573G>A

1 paper

NM_201630.2

p.P549H

c.1646C>A

1 paper

NM_201630.2

p.R485Q

c.1454G>A

1 paper

NM_201630.2

p.T551I

c.1652C>T

2 papers

NM_201630.2

p.Y477C

c.1430A>G

1 paper

NM_201630.2

p.R472K

c.1415G>A

1 paper

NM_201630.2

p.A461fs

c.1381_1382fs

1 paper

NM_201630.2

p.R574H

c.1721G>A

1 paper

NM_201630.2

p.E450K

c.1348G>A

1 paper

NM_201630.2

p.T591T

c.1773G>A

1 paper

NM_201630.2

p.D603Y

c.1807G>T