Varaico: Literature-Extracted Genetic Variants

LRRN2

69 papers

RefSeq Summary

The protein encoded by this gene belongs to the leucine-rich repeat superfamily. This gene was found to be amplified and overexpressed in malignant gliomas. The encoded protein has homology with other...

Pfam Domains

LRR_8aa 93–153UCSCLeucine rich repeat

LRR_8aa 213–273UCSCLeucine rich repeat

LRR_8aa 310–371UCSCLeucine rich repeat

I-setaa 427–514UCSCImmunoglobulin I-set domain

Gene Aliases

HGNC Name

leucine rich repeat neuronal 2

HGNC Previous Symbol

LRRN5

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_201630.2

p.P431fs

c.1291_1292fs

Surrounding Variants

1 paper

NM_201630.2

p.R427Q

c.1280G>A

1 paper

NM_201630.2

p.R414W

c.1240C>T

1 paper

NM_201630.2

p.E450K

c.1348G>A

1 paper

NM_201630.2

p.P407L

c.1220C>T

1 paper

NM_201630.2

p.A461fs

c.1381_1382fs

1 paper

NM_201630.2

p.A398A

c.1194G>A

2 papers

NM_201630.2

p.P392P

c.1176G>A

1 paper

NM_201630.2

p.R472K

c.1415G>A

2 papers

NM_201630.2

p.Y477C

c.1430A>G

1 paper

NM_201630.2

p.T385T

c.1155C>A

1 paper

NM_201630.2

p.T383M

c.1148C>T

1 paper

NM_201630.2

p.T383R

c.1148C>G