Varaico: Literature-Extracted Genetic Variants

LRRN2

69 papers

RefSeq Summary

The protein encoded by this gene belongs to the leucine-rich repeat superfamily. This gene was found to be amplified and overexpressed in malignant gliomas. The encoded protein has homology with other...

Pfam Domains

LRR_8aa 93–153UCSCLeucine rich repeat

LRR_8aa 213–273UCSCLeucine rich repeat

LRR_8aa 310–371UCSCLeucine rich repeat

I-setaa 427–514UCSCImmunoglobulin I-set domain

Gene Aliases

HGNC Name

leucine rich repeat neuronal 2

HGNC Previous Symbol

LRRN5

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_201630.2

p.I317V

c.949A>G

Surrounding Variants

1 paper

NM_201630.2

p.I326S

c.977T>G

1 paper

NM_201630.2

p.R329C

c.985C>T

1 paper

NM_201630.2

p.R329H

c.986G>A

1 paper

NM_201630.2

p.L287F

c.859C>T

1 paper

NM_201630.2

p.L273fs

c.817_818fs

1 paper

NM_201630.2

p.L361L

c.1083G>T

1 paper

NM_201630.2

p.Q362*

c.1084C>T

1 paper

NM_201630.2

p.V376fs

c.1126_1127fs

1 paper

NM_201630.2

p.V376delFs

c.1126_1127delAC

1 paper

NM_201630.2

p.R255Q

c.764G>A

1 paper

NM_201630.2

p.T383M

c.1148C>T

1 paper

NM_201630.2

p.T383R

c.1148C>G