Varaico: Literature-Extracted Genetic Variants

LRRN2

69 papers

RefSeq Summary

The protein encoded by this gene belongs to the leucine-rich repeat superfamily. This gene was found to be amplified and overexpressed in malignant gliomas. The encoded protein has homology with other...

Pfam Domains

LRR_8aa 93–153UCSCLeucine rich repeat

LRR_8aa 213–273UCSCLeucine rich repeat

LRR_8aa 310–371UCSCLeucine rich repeat

I-setaa 427–514UCSCImmunoglobulin I-set domain

Gene Aliases

HGNC Name

leucine rich repeat neuronal 2

HGNC Previous Symbol

LRRN5

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_201630.2

p.L140P

c.419T>C

Surrounding Variants

1 paper

NM_201630.2

p.A141P

c.421G>C

1 paper

NM_201630.2

p.S142fs

c.424_425fs

1 paper

NM_201630.2

p.A138V

c.413C>T

1 paper

NM_201630.2

p.S136R

c.408C>G

1 paper

NM_201630.2

p.S136R

c.408C>A

1 paper

NM_201630.2

p.S136R

c.406A>C

1 paper

NM_201630.2

p.Q152H

c.456G>T

1 paper

NM_201630.2

p.Q152H

c.456G>C

1 paper

NM_201630.2

p.G163D

c.488G>A

1 paper

NM_201630.2

p.R109Q

c.326G>A

1 paper

NM_201630.2

p.N103I

c.308A>T

1 paper

NM_201630.2

p.I180T

c.539T>C