Varaico: Literature-Extracted Genetic Variants

LRRN2

69 papers

RefSeq Summary

The protein encoded by this gene belongs to the leucine-rich repeat superfamily. This gene was found to be amplified and overexpressed in malignant gliomas. The encoded protein has homology with other...

Pfam Domains

LRR_8aa 93–153UCSCLeucine rich repeat

LRR_8aa 213–273UCSCLeucine rich repeat

LRR_8aa 310–371UCSCLeucine rich repeat

I-setaa 427–514UCSCImmunoglobulin I-set domain

Gene Aliases

HGNC Name

leucine rich repeat neuronal 2

HGNC Previous Symbol

LRRN5

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_201630.2

p.L74P

c.221T>C

Surrounding Variants

1 paper

NM_201630.2

p.P65P

c.195G>A

1 paper

NM_201630.2

p.Y91C

c.272A>G

1 paper

NM_201630.2

p.D57N

c.169G>A

1 paper

NM_201630.2

p.D54N

c.160G>A

1 paper

NM_201630.2

p.D99H

c.295G>C

1 paper

NM_201630.2

p.E49K

c.145G>A

1 paper

NM_201630.2

p.N103I

c.308A>T

1 paper

NM_201630.2

p.S45A

c.133T>G

1 paper

NM_201630.2

p.R44L

c.131G>T

2 papers

NM_201630.2

p.T42M

c.125C>T

1 paper

NM_201630.2

p.R109Q

c.326G>A

1 paper

NM_201630.2

p.C33Y

c.98G>A