limbic system associated membrane protein

IGLON3

limbic system-associated membrane protein

IgLON family member 3

Limbic system-associated membrane protein

This gene encodes a member of the immunoglobulin LAMP, OBCAM and neurotrimin (IgLON) family of proteins. The encoded preproprotein is proteolytically processed to generate a neuronal surface glycoprotein. This protein may act as a selective homophilic adhesion molecule during axon guidance and neuronal growth in the developing limbic system. The encoded protein may also function as a tumor suppressor and may play a role in neuropsychiatric disorders. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed. [provided by RefSeq, Jan 2016].

Varaico: Literature-Extracted Genetic Variants

LSAMP

RefSeq Summary

Pfam Domains

Gene Aliases

HGNC Name

HGNC Alias Symbol