Varaico: Literature-Extracted Genetic Variants

LTK

168 papers

RefSeq Summary

The protein encoded by this gene is a member of the ros/insulin receptor family of tyrosine kinases. Tyrosine-specific phosphorylation of proteins is a key to the control of diverse pathways leading t...

Pfam Domains

ALK_LTK_GRDaa 113–383UCSCALK/LTK, Glycine-rich domain

PK_Tyr_Ser-Thraa 510–777UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

leukocyte receptor tyrosine kinase

HGNC Alias Symbol

TYK1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002344.6

p.L590M

c.1768C>A

Surrounding Variants

1 paper

NM_002344.6

p.R586H

c.1757G>A

1 paper

NM_002344.6

p.S594A

c.1780T>G

1 paper

NM_002344.6

p.T584T

c.1752C>T

1 paper

NM_002344.6

p.T584N

c.1751C>A

2 papers

NM_002344.6

p.G596R

c.1786G>C

2 papers

NM_002344.6

p.G596R

c.1786G>A

1 paper

NM_002344.6

p.D597N

c.1789G>A

1 paper

NM_002344.6

p.R603K

c.1808G>A

1 paper

NM_002344.6

p.C576S

c.1727G>C

1 paper

NM_002344.6

p.C576S

c.1726T>A

1 paper

NM_002344.6

p.V574L

c.1720G>T

1 paper

NM_002344.6

p.V574L

c.1720G>C