Varaico: Literature-Extracted Genetic Variants

LTK

168 papers

RefSeq Summary

The protein encoded by this gene is a member of the ros/insulin receptor family of tyrosine kinases. Tyrosine-specific phosphorylation of proteins is a key to the control of diverse pathways leading t...

Pfam Domains

ALK_LTK_GRDaa 113–383UCSCALK/LTK, Glycine-rich domain

PK_Tyr_Ser-Thraa 510–777UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

leukocyte receptor tyrosine kinase

HGNC Alias Symbol

TYK1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002344.6

p.A205T

c.613G>A

Surrounding Variants

1 paper

NM_002344.6

p.A205G

c.614C>G

1 paper

NM_002344.6

p.W204L

c.611G>T

1 paper

NM_002344.6

p.W204G

c.610T>G

1 paper

NM_002344.6

p.G206E

c.617G>A

1 paper

NM_002344.6

p.G206G

c.618A>G

1 paper

NM_002344.6

p.P199P

c.597G>A

1 paper

NM_002344.6

p.G213ins3

c.638_639ins9

1 paper

NM_002344.6

p.G213Fs

c.639delinsTGGCGGFs

4 papers

NM_002344.6

p.G213delins

c.639delinsTGGCGGGGGC

1 paper

NM_002344.6

p.G213_A214ins2

c.639_640ins6

1 paper

NM_002344.6

p.G213insFs

c.638_639ins10

1 paper

NM_002344.6

p.G210_G213del0

c.630_638del9