Varaico: Literature-Extracted Genetic Variants

LYN

213 papers

RefSeq Summary

This gene encodes a tyrosine protein kinase, which maybe involved in the regulation of mast cell degranulation, and erythroid differentiation. Alternatively spliced transcript variants encoding differ...

Pfam Domains

SH3_1aa 69–115UCSCSH3 domain

SH2aa 129–211UCSCSH2 domain

PK_Tyr_Ser-Thraa 247–497UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

LYN proto-oncogene, Src family tyrosine kinase

HGNC Alias Symbol

JTK8

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002350.4

p.D18V

c.53A>T

Surrounding Variants

1 paper

NM_002350.4

p.D15N

c.43G>A

1 paper

NM_002350.4

p.R25H

c.74G>A

1 paper

NM_002350.4

p.D10A

c.29A>C

2 papers

NM_002350.4

p.E28K

c.82G>A

1 paper

NM_002350.4

p.E28D

c.84A>C

1 paper

NM_002350.4

p.E28D

c.84A>T

1 paper

NM_002350.4

p.E28_R29delins

c.84_85delinsCC

1 paper

NM_002350.4

p.K7fs

c.19_20fs

1 paper

NM_002350.4

p.K7delFs

c.21delA

1 paper

NM_002350.4

p.Y32F

c.95A>T

1 paper

NM_002350.4

p.G2R

c.4G>A

1 paper

NM_002350.4

p.G2R

c.4G>C