Varaico: Literature-Extracted Genetic Variants

LYN

213 papers

RefSeq Summary

This gene encodes a tyrosine protein kinase, which maybe involved in the regulation of mast cell degranulation, and erythroid differentiation. Alternatively spliced transcript variants encoding differ...

Pfam Domains

SH3_1aa 69–115UCSCSH3 domain

SH2aa 129–211UCSCSH2 domain

PK_Tyr_Ser-Thraa 247–497UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

LYN proto-oncogene, Src family tyrosine kinase

HGNC Alias Symbol

JTK8

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002350.4

p.W129*

c.386G>A

Surrounding Variants

1 paper

NM_002350.4

p.W129*

c.387G>A

1 paper

NM_002350.4

p.F130I

c.388T>A

2 papers

NM_002350.4

p.A139T

c.415G>A

1 paper

NM_002350.4

p.A139E

c.416C>A

1 paper

NM_002350.4

p.Q142H

c.426G>C

1 paper

NM_002350.4

p.A145P

c.433G>C

1 paper

NM_002350.4

p.N148H

c.442A>C

1 paper

NM_002350.4

p.A150T

c.448G>A

2 papers

NM_002350.4

p.L154F

c.460C>T

2 papers

NM_002350.4

p.E159K

c.475G>A

1 paper

NM_002350.4

p.T160K

c.479C>A

1 paper

NM_002350.4

p.T160R

c.479C>G