Varaico: Literature-Extracted Genetic Variants

LYN

213 papers

RefSeq Summary

This gene encodes a tyrosine protein kinase, which maybe involved in the regulation of mast cell degranulation, and erythroid differentiation. Alternatively spliced transcript variants encoding differ...

Pfam Domains

SH3_1aa 69–115UCSCSH3 domain

SH2aa 129–211UCSCSH2 domain

PK_Tyr_Ser-Thraa 247–497UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

LYN proto-oncogene, Src family tyrosine kinase

HGNC Alias Symbol

JTK8

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002350.4

p.G354E

c.1061G>A

Surrounding Variants

1 paper

NM_002350.4

p.R360W

c.1078C>T

1 paper

NM_002350.4

p.R360Q

c.1079G>A

1 paper

NM_002350.4

p.Y363*

c.1089C>A

1 paper

NM_002350.4

p.Y363*

c.1089C>G

1 paper

NM_002350.4

p.R366W

c.1096C>T

2 papers

NM_002350.4

p.A370T

c.1108G>A

1 paper

NM_002350.4

p.A371V

c.1112C>T

1 paper

NM_002350.4

p.M380fs

c.1138_1139fs

1 paper

NM_002350.4

p.C381Y

c.1142G>A

1 paper

NM_002350.4

p.C381*

c.1143C>A

4 papers

NM_002350.4

p.D385Y

c.1153G>T

2 papers

NM_002350.4

p.D385G

c.1154A>G