Varaico: Literature-Extracted Genetic Variants

LYPLA1

30 papers

RefSeq Summary

This gene encodes a member of the alpha/beta hydrolase superfamily. The encoded protein functions as a homodimer, exhibiting both depalmitoylating as well as lysophospholipase activity, and may be inv...

Pfam Domains

Abhydrolase_2aa 1–162UCSCPhospholipase/Carboxylesterase

Abhydrolase_2aa 8–125UCSCPhospholipase/Carboxylesterase

Abhydrolase_2aa 123–192UCSCPhospholipase/Carboxylesterase

Gene Aliases

HGNC Name

lysophospholipase 1

HGNC Alias Symbols

LPL1; APT-1; APT1

Papers

RefSeq ID

Protein change

DNA change

1–12 of 28 variants

3 papers

NM_006330.4

p.S119A

c.355T>G

2 papers

NM_006330.4

p.L176M

c.526T>A

2 papers

NM_006330.4

p.K224R

c.671A>G

1 paper

NM_006330.4

p.M1insFs

c.1_2insT

1 paper

NM_006330.4

p.M1_C2insT

c.1_5ins3

1 paper

NM_006330.4

p.M1I

c.3G>T

1 paper

NM_006330.4

p.M1insFs

c.2_3insT

1 paper

NM_006330.4

p.M1I

c.3G>C

1 paper

NM_006330.4

p.M1I

c.3G>A

1 paper

NM_006330.4

p.T8S

c.22A>T

1 paper

NM_006330.4

p.I13V

c.37A>G

1 paper

NM_006330.4

p.T21A

c.61A>G