Varaico: Literature-Extracted Genetic Variants

Gene:MAP2K1
Variant:p.K4N

MAP2K1

1,996 papers

RefSeq Summary

The protein encoded by this gene is a member of the dual specificity protein kinase family, which acts as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular sign...

Pfam Domains

Pkinaseaa 46–127UCSCProtein kinase domain
Pkinaseaa 123–313UCSCProtein kinase domain

Gene Aliases

HGNC Name

mitogen-activated protein kinase kinase 1

HGNC Previous Symbol

PRKMK1

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
33 papers
NM_002755.4
p.K4N
c.12G>C
Surrounding Variants
23 papers
NM_002755.4
p.K4K
c.12G>A
2 papers
NM_002755.4
p.K4N
c.12G>T
2 papers
NM_002755.4
p.K5E
c.13A>G
2 papers
NM_002755.4
p.K4M
c.11A>T
2 papers
NM_002755.4
p.K5N
c.15G>C
2 papers
NM_002755.4
p.K5N
c.15G>T
3 papers
NM_002755.4
p.K3M
c.8A>T
1 paper
NM_002755.4
p.K3*
c.7A>T
1 paper
NM_002755.4
p.T7fs
c.19_20fs
1 paper
NM_002755.4
p.T7A
c.19A>G
1 paper
NM_002755.4
p.T7K
c.20C>A
1 paper
NM_002755.4
p.P2S
c.4C>T
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."