Varaico: Literature-Extracted Genetic Variants

Gene:MAP2K1
Variant:p.L11M

MAP2K1

1,996 papers

RefSeq Summary

The protein encoded by this gene is a member of the dual specificity protein kinase family, which acts as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular sign...

Pfam Domains

Pkinaseaa 46–127UCSCProtein kinase domain
Pkinaseaa 123–313UCSCProtein kinase domain

Gene Aliases

HGNC Name

mitogen-activated protein kinase kinase 1

HGNC Previous Symbol

PRKMK1

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_002755.4
p.L11M
c.31C>A
Surrounding Variants
2 papers
NM_002755.4
p.Q10_L11insFs
c.30_31insC
1 paper
NM_002755.4
p.L11delFs
c.33delG
1 paper
NM_002755.4
p.Q10L
c.29A>T
1 paper
NM_002755.4
p.Q10*
c.28C>T
1 paper
NM_002755.4
p.I9M
c.27C>G
1 paper
NM_002755.4
p.I9ins1
c.26_27insGGT
1 paper
NM_002755.4
p.P13L
c.38C>T
1 paper
NM_002755.4
p.P13delins
c.38_39delinsAA
1 paper
NM_002755.4
p.P13delins
c.38_39delinsTT
1 paper
NM_002755.4
p.P8R
c.23C>G
1 paper
NM_002755.4
p.P8fs
c.22_23fs
2 papers
NM_002755.4
p.A14T
c.40G>A
UCSC Genome Browser·Imprint·Privacy·Terms·Feedback·Email Updates·

Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."