Varaico: Literature-Extracted Genetic Variants

Gene:MAP2K1
Variant:p.D16fs

MAP2K1

1,996 papers

RefSeq Summary

The protein encoded by this gene is a member of the dual specificity protein kinase family, which acts as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular sign...

Pfam Domains

Pkinaseaa 46–127UCSCProtein kinase domain
Pkinaseaa 123–313UCSCProtein kinase domain

Gene Aliases

HGNC Name

mitogen-activated protein kinase kinase 1

HGNC Previous Symbol

PRKMK1

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
3 papers
NM_002755.4
p.D16fs
c.46_47fs
Surrounding Variants
1 paper
NM_002755.4
p.G17V
c.50G>T
1 paper
NM_002755.4
p.S18delFs
c.53_54delCT
1 paper
NM_002755.4
p.A14D
c.41C>A
1 paper
NM_002755.4
p.A14_A19delFs
c.42_57del16
1 paper
NM_002755.4
p.A14_V20delFs
c.42_58del17
2 papers
NM_002755.4
p.A14T
c.40G>A
1 paper
NM_002755.4
p.A14insFs
c.40_41insC
1 paper
NM_002755.4
p.A14S
c.40G>T
3 papers
NM_002755.4
p.P15delFs
c.45delC
1 paper
NM_002755.4
p.A14fs
c.40_41fs
1 paper
NM_002755.4
p.S18T
c.52T>A
1 paper
NM_002755.4
p.S18_A19ins6
c.54_55ins18
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."