Varaico: Literature-Extracted Genetic Variants

Gene:MAP2K1
Variant:p.N78Y

MAP2K1

1,996 papers

RefSeq Summary

The protein encoded by this gene is a member of the dual specificity protein kinase family, which acts as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular sign...

Pfam Domains

Pkinaseaa 46–127UCSCProtein kinase domain
Pkinaseaa 123–313UCSCProtein kinase domain

Gene Aliases

HGNC Name

mitogen-activated protein kinase kinase 1

HGNC Previous Symbol

PRKMK1

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
2 papers
NM_002755.4
p.N78Y
c.232A>T
Surrounding Variants
1 paper
NM_002755.4
p.N78insFs
c.234dupT
3 papers
NM_002755.4
p.N78S
c.233A>G
1 paper
NM_002755.4
p.G77_N78insFs
c.231_232insAG
1 paper
NM_002755.4
p.G77D
c.230G>A
1 paper
NM_002755.4
p.G77A
c.230G>C
1 paper
NM_002755.4
p.G79S
c.235G>A
1 paper
NM_002755.4
p.G79C
c.235G>T
1 paper
NM_002755.4
p.G79D
c.236G>A
2 papers
NM_002755.4
p.G79V
c.236G>T
3 papers
NM_002755.4
p.A76V
c.227C>T
4 papers
NM_002755.4
p.G80S
c.238G>A
1 paper
NM_002755.4
p.A76T
c.226G>A
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."