Varaico: Literature-Extracted Genetic Variants

Gene:MAP2K1
Variant:p.L92R

MAP2K1

1,996 papers

RefSeq Summary

The protein encoded by this gene is a member of the dual specificity protein kinase family, which acts as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular sign...

Pfam Domains

Pkinaseaa 46–127UCSCProtein kinase domain
Pkinaseaa 123–313UCSCProtein kinase domain

Gene Aliases

HGNC Name

mitogen-activated protein kinase kinase 1

HGNC Previous Symbol

PRKMK1

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
2 papers
NM_002755.4
p.L92R
c.275T>G
Surrounding Variants
2 papers
NM_002755.4
p.V93I
c.277G>A
2 papers
NM_002755.4
p.V93F
c.277G>T
1 paper
NM_002755.4
p.V93A
c.278T>C
2 papers
NM_002755.4
p.M94V
c.280A>G
3 papers
NM_002755.4
p.M94I
c.282G>A
3 papers
NM_002755.4
p.M94I
c.282G>C
3 papers
NM_002755.4
p.M94I
c.282G>T
1 paper
NM_002755.4
p.A95T
c.283G>A
1 paper
NM_002755.4
p.P89L
c.266C>T
2 papers
NM_002755.4
p.P89T
c.265C>A
1 paper
NM_002755.4
p.K88R
c.263A>G
2 papers
NM_002755.4
p.R96K
c.287G>A
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."