Varaico: Literature-Extracted Genetic Variants

Gene:MAP2K1
Variant:p.L118P

MAP2K1

1,996 papers

RefSeq Summary

The protein encoded by this gene is a member of the dual specificity protein kinase family, which acts as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular sign...

Pfam Domains

Pkinaseaa 46–127UCSCProtein kinase domain
Pkinaseaa 123–313UCSCProtein kinase domain

Gene Aliases

HGNC Name

mitogen-activated protein kinase kinase 1

HGNC Previous Symbol

PRKMK1

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_002755.4
p.L118P
c.353T>C
Surrounding Variants
2 papers
NM_002755.4
p.L118V
c.352C>G
1 paper
NM_002755.4
p.L118L
c.354G>T
19 papers
NM_002755.4
p.H119Y
c.355C>T
3 papers
NM_002755.4
p.H119P
c.356A>C
1 paper
NM_002755.4
p.H119R
c.356A>G
1 paper
NM_002755.4
p.V117A
c.350T>C
2 papers
NM_002755.4
p.H119Q
c.357T>A
2 papers
NM_002755.4
p.H119Q
c.357T>G
3 papers
NM_002755.4
p.E120Q
c.358G>C
3 papers
NM_002755.4
p.Q116L
c.347A>T
1 paper
NM_002755.4
p.Q116K
c.346C>A
5 papers
NM_002755.4
p.E120D
c.360G>C
UCSC Genome Browser·Imprint·Privacy·Terms·Feedback·Email Updates·

Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."