Varaico: Literature-Extracted Genetic Variants

Gene:MAP2K1
Variant:p.P124S

MAP2K1

1,996 papers

RefSeq Summary

The protein encoded by this gene is a member of the dual specificity protein kinase family, which acts as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular sign...

Pfam Domains

Pkinaseaa 46–127UCSCProtein kinase domain
Pkinaseaa 123–313UCSCProtein kinase domain

Gene Aliases

HGNC Name

mitogen-activated protein kinase kinase 1

HGNC Previous Symbol

PRKMK1

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
102 papers
NM_002755.4
p.P124S
c.370C>T
Surrounding Variants
4 papers
NM_002755.4
p.P124T
c.370C>A
2 papers
NM_002755.4
p.P124A
c.370C>G
1 paper
NM_002755.4
p.P124delins
c.370_371delinsTT
28 papers
NM_002755.4
p.P124Q
c.371C>A
15 papers
NM_002755.4
p.P124R
c.371C>G
115 papers
NM_002755.4
p.P124L
c.371C>T
2 papers
NM_002755.4
p.S123F
c.368C>T
1 paper
NM_002755.4
p.S123T
c.367T>A
2 papers
NM_002755.4
p.S123P
c.367T>C
1 paper
NM_002755.4
p.Y125H
c.373T>C
1 paper
NM_002755.4
p.S123A
c.367T>G
3 papers
NM_002755.4
p.Y125C
c.374A>G
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."