Varaico: Literature-Extracted Genetic Variants

Gene:MAP2K1
Variant:p.F129Y

MAP2K1

1,996 papers

RefSeq Summary

The protein encoded by this gene is a member of the dual specificity protein kinase family, which acts as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular sign...

Pfam Domains

Pkinaseaa 46–127UCSCProtein kinase domain
Pkinaseaa 123–313UCSCProtein kinase domain

Gene Aliases

HGNC Name

mitogen-activated protein kinase kinase 1

HGNC Previous Symbol

PRKMK1

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_002755.4
p.F129Y
c.386T>A
Surrounding Variants
1 paper
NM_002755.4
p.F129S
c.386T>C
26 papers
NM_002755.4
p.F129L
c.387C>A
26 papers
NM_002755.4
p.F129L
c.387C>G
1 paper
NM_002755.4
p.F129I
c.385T>A
26 papers
NM_002755.4
p.F129L
c.385T>C
1 paper
NM_002755.4
p.G128G
c.384C>G
6 papers
NM_002755.4
p.Y130N
c.388T>A
16 papers
NM_002755.4
p.Y130H
c.388T>C
135 papers
NM_002755.4
p.Y130C
c.389A>G
1 paper
NM_002755.4
p.Y130F
c.389A>T
46 papers
NM_002755.4
p.G128D
c.383G>A
4 papers
NM_002755.4
p.G128A
c.383G>C
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."