Varaico: Literature-Extracted Genetic Variants

Gene:MAP2K1
Variant:p.K192N

MAP2K1

1,996 papers

RefSeq Summary

The protein encoded by this gene is a member of the dual specificity protein kinase family, which acts as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular sign...

Pfam Domains

Pkinaseaa 46–127UCSCProtein kinase domain
Pkinaseaa 123–313UCSCProtein kinase domain

Gene Aliases

HGNC Name

mitogen-activated protein kinase kinase 1

HGNC Previous Symbol

PRKMK1

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_002755.4
p.K192N
c.576G>C
Surrounding Variants
1 paper
NM_002755.4
p.K192N
c.576G>T
1 paper
NM_002755.4
p.P193delFs
c.578delC
1 paper
NM_002755.4
p.P193A
c.577C>G
5 papers
NM_002755.4
p.P193S
c.577C>T
2 papers
NM_002755.4
p.S194P
c.580T>C
2 papers
NM_002755.4
p.S194A
c.580T>G
1 paper
NM_002755.4
p.N195S
c.584A>G
1 paper
NM_002755.4
p.I196V
c.586A>G
1 paper
NM_002755.4
p.L197I
c.589C>A
1 paper
NM_002755.4
p.L197V
c.589C>G
3 papers
NM_002755.4
p.N199S
c.596A>G
1 paper
NM_002755.4
p.S200P
c.598T>C
UCSC Genome Browser·Imprint·Privacy·Terms·Feedback·Email Updates·

Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."