Varaico: Literature-Extracted Genetic Variants

Gene:MAP2K1
Variant:p.K205N

MAP2K1

1,996 papers

RefSeq Summary

The protein encoded by this gene is a member of the dual specificity protein kinase family, which acts as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular sign...

Pfam Domains

Pkinaseaa 46–127UCSCProtein kinase domain
Pkinaseaa 123–313UCSCProtein kinase domain

Gene Aliases

HGNC Name

mitogen-activated protein kinase kinase 1

HGNC Previous Symbol

PRKMK1

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_002755.4
p.K205N
c.615G>C
Surrounding Variants
1 paper
NM_002755.4
p.K205N
c.615G>T
2 papers
NM_002755.4
p.L206I
c.616C>A
2 papers
NM_002755.4
p.L206F
c.616C>T
1 paper
NM_002755.4
p.L206R
c.617T>G
1 paper
NM_002755.4
p.I204M
c.612C>G
4 papers
NM_002755.4
p.I204T
c.611T>C
1 paper
NM_002755.4
p.I204F
c.610A>T
1 paper
NM_002755.4
p.I204fs
c.610_611fs
1 paper
NM_002755.4
p.E203E
c.609G>A
1 paper
NM_002755.4
p.E203D
c.609G>C
1 paper
NM_002755.4
p.E203D
c.609G>T
1 paper
NM_002755.4
p.E203insFs
c.609dupG
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."