Varaico: Literature-Extracted Genetic Variants

Gene:MAP2K2
Variant:p.G286R

MAP2K2

741 papers

RefSeq Summary

The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is known to play a critical role in mitogen growth factor signal transdu...

Pfam Domains

Pkinaseaa 72–369UCSCProtein kinase domain

Gene Aliases

HGNC Name

mitogen-activated protein kinase kinase 2

HGNC Previous Symbol

PRKMK2

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
5 papers
NM_030662.4
p.G286R
c.856G>C
Surrounding Variants
5 papers
NM_030662.4
p.G286R
c.856G>A
1 paper
NM_030662.4
p.D285D
c.855C>T
1 paper
NM_030662.4
p.D285delFs
c.854delT
1 paper
NM_030662.4
p.E287*
c.859G>T
1 paper
NM_030662.4
p.D285N
c.853G>A
1 paper
NM_030662.4
p.D285fs
c.853_854fs
1 paper
NM_030662.4
p.V283E
c.848T>A
2 papers
NM_030662.4
p.V283L
c.847G>T
2 papers
NM_030662.4
p.V283L
c.847G>C
1 paper
NM_030662.4
p.G289R
c.865G>C
3 papers
NM_030662.4
p.V283M
c.847G>A
1 paper
NM_030662.4
p.G289R
c.865G>A
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