Varaico: Literature-Extracted Genetic Variants

Gene:MAP2K2
Variant:p.V283M

MAP2K2

741 papers

RefSeq Summary

The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is known to play a critical role in mitogen growth factor signal transdu...

Pfam Domains

Pkinaseaa 72–369UCSCProtein kinase domain

Gene Aliases

HGNC Name

mitogen-activated protein kinase kinase 2

HGNC Previous Symbol

PRKMK2

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
3 papers
NM_030662.4
p.V283M
c.847G>A
Surrounding Variants
2 papers
NM_030662.4
p.V283L
c.847G>T
2 papers
NM_030662.4
p.V283L
c.847G>C
1 paper
NM_030662.4
p.V283E
c.848T>A
2 papers
NM_030662.4
p.P282P
c.846C>T
2 papers
NM_030662.4
p.P282S
c.844C>T
2 papers
NM_030662.4
p.E276_R281delFs
c.827_843del17
1 paper
NM_030662.4
p.R281P
c.842G>C
1 paper
NM_030662.4
p.R281Q
c.842G>A
1 paper
NM_030662.4
p.D285N
c.853G>A
3 papers
NM_030662.4
p.R281W
c.841C>T
1 paper
NM_030662.4
p.D285fs
c.853_854fs
1 paper
NM_030662.4
p.D285D
c.855C>T
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