Varaico: Literature-Extracted Genetic Variants

Gene:MAP2K2
Variant:p.F279S

MAP2K2

741 papers

RefSeq Summary

The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is known to play a critical role in mitogen growth factor signal transdu...

Pfam Domains

Pkinaseaa 72–369UCSCProtein kinase domain

Gene Aliases

HGNC Name

mitogen-activated protein kinase kinase 2

HGNC Previous Symbol

PRKMK2

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_030662.4
p.F279S
c.836T>C
Surrounding Variants
2 papers
NM_030662.4
p.G280R
c.838G>C
1 paper
NM_030662.4
p.I278M
c.834C>G
3 papers
NM_030662.4
p.R281W
c.841C>T
1 paper
NM_030662.4
p.R281P
c.842G>C
1 paper
NM_030662.4
p.R281Q
c.842G>A
1 paper
NM_030662.4
p.A277T
c.829G>A
2 papers
NM_030662.4
p.E276fs
c.826_827fs
2 papers
NM_030662.4
p.P282S
c.844C>T
2 papers
NM_030662.4
p.E276_R281delFs
c.827_843del17
1 paper
NM_030662.4
p.E276Q
c.826G>C
2 papers
NM_030662.4
p.P282P
c.846C>T
2 papers
NM_030662.4
p.V283L
c.847G>T
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."