Varaico: Literature-Extracted Genetic Variants

Gene:MAP2K2
Variant:p.E276fs

MAP2K2

741 papers

RefSeq Summary

The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is known to play a critical role in mitogen growth factor signal transdu...

Pfam Domains

Pkinaseaa 72–369UCSCProtein kinase domain

Gene Aliases

HGNC Name

mitogen-activated protein kinase kinase 2

HGNC Previous Symbol

PRKMK2

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
2 papers
NM_030662.4
p.E276fs
c.826_827fs
Surrounding Variants
1 paper
NM_030662.4
p.A277T
c.829G>A
1 paper
NM_030662.4
p.E276Q
c.826G>C
1 paper
NM_030662.4
p.I278M
c.834C>G
1 paper
NM_030662.4
p.F279S
c.836T>C
1 paper
NM_030662.4
p.K273insFs
c.817dupA
2 papers
NM_030662.4
p.G280R
c.838G>C
8 papers
NM_030662.4
p.K273R
c.818A>G
3 papers
NM_030662.4
p.R281W
c.841C>T
1 paper
NM_030662.4
p.R281P
c.842G>C
1 paper
NM_030662.4
p.R281Q
c.842G>A
1 paper
NM_030662.4
p.A272T
c.814G>A
1 paper
NM_030662.4
p.D271E
c.813C>G
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