Varaico: Literature-Extracted Genetic Variants

Gene:MAP2K2
Variant:p.K273insFs

MAP2K2

741 papers

RefSeq Summary

The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is known to play a critical role in mitogen growth factor signal transdu...

Pfam Domains

Pkinaseaa 72–369UCSCProtein kinase domain

Gene Aliases

HGNC Name

mitogen-activated protein kinase kinase 2

HGNC Previous Symbol

PRKMK2

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_030662.4
p.K273insFs
c.817dupA
Surrounding Variants
8 papers
NM_030662.4
p.K273R
c.818A>G
1 paper
NM_030662.4
p.E276Q
c.826G>C
1 paper
NM_030662.4
p.A272T
c.814G>A
1 paper
NM_030662.4
p.D271E
c.813C>G
1 paper
NM_030662.4
p.D271E
c.813C>A
2 papers
NM_030662.4
p.E276fs
c.826_827fs
1 paper
NM_030662.4
p.P270insFs
c.810dupC
1 paper
NM_030662.4
p.A277T
c.829G>A
1 paper
NM_030662.4
p.D271N
c.811G>A
1 paper
NM_030662.4
p.P270delFs
c.808_809delGG
1 paper
NM_030662.4
p.P270P
c.810C>T
1 paper
NM_030662.4
p.P270R
c.809C>G
UCSC Genome Browser·Imprint·Privacy·Terms·Feedback·Email Updates·

Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."