Varaico: Literature-Extracted Genetic Variants

Gene:MAP2K2
Variant:p.D271E

MAP2K2

741 papers

RefSeq Summary

The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is known to play a critical role in mitogen growth factor signal transdu...

Pfam Domains

Pkinaseaa 72–369UCSCProtein kinase domain

Gene Aliases

HGNC Name

mitogen-activated protein kinase kinase 2

HGNC Previous Symbol

PRKMK2

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_030662.4
p.D271E
c.813C>A
Surrounding Variants
1 paper
NM_030662.4
p.D271E
c.813C>G
1 paper
NM_030662.4
p.A272T
c.814G>A
1 paper
NM_030662.4
p.P270insFs
c.810dupC
1 paper
NM_030662.4
p.D271N
c.811G>A
1 paper
NM_030662.4
p.P270delFs
c.808_809delGG
1 paper
NM_030662.4
p.P270P
c.810C>T
1 paper
NM_030662.4
p.P270R
c.809C>G
1 paper
NM_030662.4
p.P270fs
c.808_809fs
8 papers
NM_030662.4
p.K273R
c.818A>G
1 paper
NM_030662.4
p.K273insFs
c.817dupA
8 papers
NM_030662.4
p.P269L
c.806C>T
3 papers
NM_030662.4
p.P269R
c.806C>G
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