Varaico: Literature-Extracted Genetic Variants

Gene:MAP2K2
Variant:p.V215L

MAP2K2

741 papers

RefSeq Summary

The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is known to play a critical role in mitogen growth factor signal transdu...

Pfam Domains

Pkinaseaa 72–369UCSCProtein kinase domain

Gene Aliases

HGNC Name

mitogen-activated protein kinase kinase 2

HGNC Previous Symbol

PRKMK2

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_030662.4
p.V215L
c.643G>T
Surrounding Variants
1 paper
NM_030662.4
p.V215L
c.643G>C
1 paper
NM_030662.4
p.V215M
c.643G>A
6 papers
NM_030662.4
p.V215E
c.644T>A
1 paper
NM_030662.4
p.G214R
c.640G>C
1 paper
NM_030662.4
p.G214R
c.640G>A
1 paper
NM_030662.4
p.F213C
c.638T>G
1 paper
NM_030662.4
p.F213_G214insT
c.637_641ins3
1 paper
NM_030662.4
p.F213I
c.637T>A
1 paper
NM_030662.4
p.Q218*
c.652C>T
1 paper
NM_030662.4
p.Q218P
c.653A>C
2 papers
NM_030662.4
p.Q218delFs
c.652delG
1 paper
NM_030662.4
p.Q218H
c.654G>T
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."