Varaico: Literature-Extracted Genetic Variants

Gene:MAP2K2
Variant:p.D140D

MAP2K2

741 papers

RefSeq Summary

The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is known to play a critical role in mitogen growth factor signal transdu...

Pfam Domains

Pkinaseaa 72–369UCSCProtein kinase domain

Gene Aliases

HGNC Name

mitogen-activated protein kinase kinase 2

HGNC Previous Symbol

PRKMK2

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_030662.4
p.D140D
c.420C>T
Surrounding Variants
1 paper
NM_030662.4
p.D140H
c.418G>C
1 paper
NM_030662.4
p.S139R
c.417T>G
1 paper
NM_030662.4
p.S139R
c.417T>A
1 paper
NM_030662.4
p.S139N
c.416G>A
1 paper
NM_030662.4
p.S139R
c.415A>C
1 paper
NM_030662.4
p.Y138N
c.412T>A
1 paper
NM_030662.4
p.A136fs
c.406_407fs
1 paper
NM_030662.4
p.I145V
c.433A>G
1 paper
NM_030662.4
p.A136T
c.406G>A
1 paper
NM_030662.4
p.G135_A136insFs
c.405_406insC
1 paper
NM_030662.4
p.G135G
c.405G>C
1 paper
NM_030662.4
p.G135A
c.404G>C
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