Varaico: Literature-Extracted Genetic Variants

Gene:MAP2K2
Variant:p.H123Q

MAP2K2

741 papers

RefSeq Summary

The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is known to play a critical role in mitogen growth factor signal transdu...

Pfam Domains

Pkinaseaa 72–369UCSCProtein kinase domain

Gene Aliases

HGNC Name

mitogen-activated protein kinase kinase 2

HGNC Previous Symbol

PRKMK2

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
2 papers
NM_030662.4
p.H123Q
c.369C>A
Surrounding Variants
2 papers
NM_030662.4
p.H123Q
c.369C>G
1 paper
NM_030662.4
p.E124K
c.370G>A
1 paper
NM_030662.4
p.H123L
c.368A>T
1 paper
NM_030662.4
p.H123Y
c.367C>T
1 paper
NM_030662.4
p.H123N
c.367C>A
1 paper
NM_030662.4
p.E124G
c.371A>G
16 papers
NM_030662.4
p.C125S
c.373T>A
1 paper
NM_030662.4
p.E124delFs
c.371_372delTT
16 papers
NM_030662.4
p.C125S
c.374G>C
8 papers
NM_030662.4
p.N126D
c.376A>G
1 paper
NM_030662.4
p.N126H
c.376A>C
1 paper
NM_030662.4
p.V121I
c.361G>A
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