Varaico: Literature-Extracted Genetic Variants

Gene:MAP2K2
Variant:p.Q114H

MAP2K2

741 papers

RefSeq Summary

The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is known to play a critical role in mitogen growth factor signal transdu...

Pfam Domains

Pkinaseaa 72–369UCSCProtein kinase domain

Gene Aliases

HGNC Name

mitogen-activated protein kinase kinase 2

HGNC Previous Symbol

PRKMK2

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_030662.4
p.Q114H
c.342G>C
Surrounding Variants
1 paper
NM_030662.4
p.Q114H
c.342G>T
1 paper
NM_030662.4
p.I115V
c.343A>G
1 paper
NM_030662.4
p.I115N
c.344T>A
2 papers
NM_030662.4
p.R112L
c.335G>T
2 papers
NM_030662.4
p.R112Q
c.335G>A
2 papers
NM_030662.4
p.R117C
c.349C>T
2 papers
NM_030662.4
p.R117H
c.350G>A
1 paper
NM_030662.4
p.R112W
c.334C>T
1 paper
NM_030662.4
p.R117R
c.351C>G
1 paper
NM_030662.4
p.I111M
c.333C>G
1 paper
NM_030662.4
p.E118A
c.353A>C
2 papers
NM_030662.4
p.A110V
c.329C>T
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