Varaico: Literature-Extracted Genetic Variants

Gene:MAP2K2
Variant:p.P109L

MAP2K2

741 papers

RefSeq Summary

The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is known to play a critical role in mitogen growth factor signal transdu...

Pfam Domains

Pkinaseaa 72–369UCSCProtein kinase domain

Gene Aliases

HGNC Name

mitogen-activated protein kinase kinase 2

HGNC Previous Symbol

PRKMK2

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_030662.4
p.P109L
c.326C>T
Surrounding Variants
2 papers
NM_030662.4
p.P109S
c.325C>T
1 paper
NM_030662.4
p.P109A
c.325C>G
1 paper
NM_030662.4
p.K108fs
c.322_323fs
2 papers
NM_030662.4
p.A110V
c.329C>T
1 paper
NM_030662.4
p.L102_I107del0
c.304_321del18
2 papers
NM_030662.4
p.I107N
c.320T>A
1 paper
NM_030662.4
p.I111M
c.333C>G
1 paper
NM_030662.4
p.R112W
c.334C>T
2 papers
NM_030662.4
p.R112L
c.335G>T
2 papers
NM_030662.4
p.R112Q
c.335G>A
1 paper
NM_030662.4
p.L105L
c.315T>G
1 paper
NM_030662.4
p.Q114H
c.342G>T
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