Varaico: Literature-Extracted Genetic Variants

Gene:MAP2K2
Variant:p.R92G

MAP2K2

741 papers

RefSeq Summary

The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is known to play a critical role in mitogen growth factor signal transdu...

Pfam Domains

Pkinaseaa 72–369UCSCProtein kinase domain

Gene Aliases

HGNC Name

mitogen-activated protein kinase kinase 2

HGNC Previous Symbol

PRKMK2

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
2 papers
NM_030662.4
p.R92G
c.274A>G
Surrounding Variants
1 paper
NM_030662.4
p.R92I
c.275G>T
1 paper
NM_030662.4
p.R92R
c.276A>G
2 papers
NM_030662.4
p.P93L
c.278C>T
1 paper
NM_030662.4
p.S94P
c.280T>C
9 papers
NM_030662.4
p.S94L
c.281C>T
1 paper
NM_030662.4
p.K88delFs
c.264delT
2 papers
NM_030662.4
p.G95A
c.284G>C
1 paper
NM_030662.4
p.K88fs
c.262_263fs
1 paper
NM_030662.4
p.L96F
c.286C>T
3 papers
NM_030662.4
p.I97F
c.289A>T
2 papers
NM_030662.4
p.T87A
c.259A>G
3 papers
NM_030662.4
p.V85G
c.254T>G
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