Varaico: Literature-Extracted Genetic Variants

Gene:MAP2K2
Variant:p.R74T

MAP2K2

741 papers

RefSeq Summary

The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is known to play a critical role in mitogen growth factor signal transdu...

Pfam Domains

Pkinaseaa 72–369UCSCProtein kinase domain

Gene Aliases

HGNC Name

mitogen-activated protein kinase kinase 2

HGNC Previous Symbol

PRKMK2

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_030662.4
p.R74T
c.221G>C
Surrounding Variants
5 papers
NM_030662.4
p.E73K
c.217G>A
1 paper
NM_030662.4
p.F72F
c.216C>T
1 paper
NM_030662.4
p.F72V
c.214T>G
1 paper
NM_030662.4
p.S76S
c.228A>C
1 paper
NM_030662.4
p.D71_F72insFs
c.213_214insT
1 paper
NM_030662.4
p.D71Y
c.211G>T
1 paper
NM_030662.4
p.D71N
c.211G>A
1 paper
NM_030662.4
p.D69del1
c.205_206delGTC
1 paper
NM_030662.4
p.D69E
c.207C>G
1 paper
NM_030662.4
p.D69E
c.207C>A
4 papers
NM_030662.4
p.A80T
c.238G>A
2 papers
NM_030662.4
p.A80V
c.239C>T
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