Varaico: Literature-Extracted Genetic Variants

Gene:MAP2K2
Variant:p.D69E

MAP2K2

741 papers

RefSeq Summary

The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is known to play a critical role in mitogen growth factor signal transdu...

Pfam Domains

Pkinaseaa 72–369UCSCProtein kinase domain

Gene Aliases

HGNC Name

mitogen-activated protein kinase kinase 2

HGNC Previous Symbol

PRKMK2

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_030662.4
p.D69E
c.207C>A
Surrounding Variants
1 paper
NM_030662.4
p.D69E
c.207C>G
1 paper
NM_030662.4
p.D69del1
c.205_206delGTC
1 paper
NM_030662.4
p.D71Y
c.211G>T
1 paper
NM_030662.4
p.D71N
c.211G>A
1 paper
NM_030662.4
p.D71_F72insFs
c.213_214insT
1 paper
NM_030662.4
p.F72V
c.214T>G
1 paper
NM_030662.4
p.F72F
c.216C>T
2 papers
NM_030662.4
p.A62_E66del0
c.186_197del12
5 papers
NM_030662.4
p.E73K
c.217G>A
1 paper
NM_030662.4
p.E66*
c.196G>T
4 papers
NM_030662.4
p.E66K
c.196G>A
1 paper
NM_030662.4
p.R74T
c.221G>C
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