Varaico: Literature-Extracted Genetic Variants

Gene:MAP2K2
Variant:p.K61R

MAP2K2

741 papers

RefSeq Summary

The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is known to play a critical role in mitogen growth factor signal transdu...

Pfam Domains

Pkinaseaa 72–369UCSCProtein kinase domain

Gene Aliases

HGNC Name

mitogen-activated protein kinase kinase 2

HGNC Previous Symbol

PRKMK2

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
3 papers
NM_030662.4
p.K61R
c.182A>G
Surrounding Variants
1 paper
NM_030662.4
p.K61I
c.182A>T
4 papers
NM_030662.4
p.K61T
c.182A>C
6 papers
NM_030662.4
p.K61N
c.183A>T
19 papers
NM_030662.4
p.K61E
c.181A>G
6 papers
NM_030662.4
p.K61N
c.183A>C
1 paper
NM_030662.4
p.A56_Q60del0
c.166_180del15
10 papers
NM_030662.4
p.A62P
c.184G>C
1 paper
NM_030662.4
p.E55_Q60del0
c.165_179del15
1 paper
NM_030662.4
p.A62G
c.185C>G
1 paper
NM_030662.4
p.F57_A62del0
c.170_184del15
2 papers
NM_030662.4
p.Q60R
c.179A>G
31 papers
NM_030662.4
p.Q60P
c.179A>C
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."