Varaico: Literature-Extracted Genetic Variants

Gene:MAP2K2
Variant:p.F57I

MAP2K2

741 papers

RefSeq Summary

The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is known to play a critical role in mitogen growth factor signal transdu...

Pfam Domains

Pkinaseaa 72–369UCSCProtein kinase domain

Gene Aliases

HGNC Name

mitogen-activated protein kinase kinase 2

HGNC Previous Symbol

PRKMK2

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
7 papers
NM_030662.4
p.F57I
c.169T>A
Surrounding Variants
16 papers
NM_030662.4
p.F57V
c.169T>G
18 papers
NM_030662.4
p.F57L
c.169T>C
35 papers
NM_030662.4
p.F57C
c.170T>G
3 papers
NM_030662.4
p.F57S
c.170T>C
2 papers
NM_030662.4
p.F57Y
c.170T>A
19 papers
NM_030662.4
p.F57L
c.171T>G
18 papers
NM_030662.4
p.F57L
c.171T>A
1 paper
NM_030662.4
p.L58L
c.174C>A
1 paper
NM_030662.4
p.R53_L58del0
c.159_173del15
1 paper
NM_030662.4
p.T59fs
c.175_176fs
1 paper
NM_030662.4
p.T59insFs
c.175dupA
1 paper
NM_030662.4
p.L54P
c.161T>C
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