Varaico: Literature-Extracted Genetic Variants

Gene:MAP2K4
Variant:p.E221*

MAP2K4

442 papers

RefSeq Summary

This gene encodes a member of the mitogen-activated protein kinase (MAPK) family. Members of this family act as an integration point for multiple biochemical signals and are involved in a wide variety...

Pfam Domains

Pkinaseaa 102–367UCSCProtein kinase domain

Gene Aliases

HGNC Name

mitogen-activated protein kinase kinase 4

HGNC Previous Symbol

SERK1

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
6 papers
NM_003010.4
p.E221*
c.661G>T
Surrounding Variants
1 paper
NM_003010.4
p.E221fs
c.661_662fs
1 paper
NM_003010.4
p.E221V
c.662A>T
1 paper
NM_003010.4
p.N222D
c.664A>G
1 paper
NM_003010.4
p.K220*
c.658A>T
1 paper
NM_003010.4
p.L219_E221delFs
c.657_661del5
1 paper
NM_003010.4
p.L219fs
c.655_656fs
1 paper
NM_003010.4
p.I225delFs
c.673delA
1 paper
NM_003010.4
p.N217K
c.651C>A
1 paper
NM_003010.4
p.N217K
c.651C>G
1 paper
NM_003010.4
p.L216L
c.648A>T
1 paper
NM_003010.4
p.H227Y
c.679C>T
1 paper
NM_003010.4
p.A215S
c.643G>T
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