Varaico: Literature-Extracted Genetic Variants

Gene:MAP2K4
Variant:p.L245F

MAP2K4

442 papers

RefSeq Summary

This gene encodes a member of the mitogen-activated protein kinase (MAPK) family. Members of this family act as an integration point for multiple biochemical signals and are involved in a wide variety...

Pfam Domains

Pkinaseaa 102–367UCSCProtein kinase domain

Gene Aliases

HGNC Name

mitogen-activated protein kinase kinase 4

HGNC Previous Symbol

SERK1

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_003010.4
p.L245F
c.733C>T
Surrounding Variants
1 paper
NM_003010.4
p.L245_C246delFs
c.733_737del5
1 paper
NM_003010.4
p.F248L
c.742T>C
1 paper
NM_003010.4
p.F248L
c.744C>A
1 paper
NM_003010.4
p.F248L
c.744C>G
1 paper
NM_003010.4
p.G249S
c.745G>A
1 paper
NM_003010.4
p.G249R
c.745G>C
2 papers
NM_003010.4
p.G241*
c.721G>T
2 papers
NM_003010.4
p.G249D
c.746G>A
2 papers
NM_003010.4
p.S240N
c.719G>A
2 papers
NM_003010.4
p.S240T
c.719G>C
1 paper
NM_003010.4
p.S240delFs
c.720delT
1 paper
NM_003010.4
p.S240fs
c.718_719fs
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."