Varaico: Literature-Extracted Genetic Variants

Gene:MAP2K5
Variant:p.M367T

MAP2K5

92 papers

RefSeq Summary

The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically interacts with and activates MAPK7/ERK5. This kinase itself...

Pfam Domains

PB1aa 18–97UCSCPB1 domain
Pkinaseaa 166–419UCSCProtein kinase domain

Gene Aliases

HGNC Name

mitogen-activated protein kinase kinase 5

HGNC Previous Symbol

PRKMK5

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
9 papers
NM_145160.3
p.M367T
c.1100T>C
Surrounding Variants
1 paper
NM_145160.3
p.M367I
c.1101G>A
1 paper
NM_145160.3
p.M367I
c.1101G>C
1 paper
NM_145160.3
p.M367I
c.1101G>T
1 paper
NM_145160.3
p.L369F
c.1105C>T
1 paper
NM_145160.3
p.C374S
c.1120T>A
1 paper
NM_145160.3
p.C374S
c.1121G>C
UCSC Genome Browser·Imprint·Privacy·Terms·Feedback·Email Updates·

Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."