Varaico: Literature-Extracted Genetic Variants

Gene:MAP2K7
Variant:p.K18M

MAP2K7

110 papers

RefSeq Summary

The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically activates MAPK8/JNK1 and MAPK9/JNK2, and this kinase itself...

Pfam Domains

Pkinaseaa 120–380UCSCProtein kinase domain

Gene Aliases

HGNC Name

mitogen-activated protein kinase kinase 7

HGNC Previous Symbol

PRKMK7

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
2 papers
NM_145185.4
p.K18M
c.53A>T
Surrounding Variants
1 paper
NM_145185.4
p.L13L
c.39G>A
1 paper
NM_145185.4
p.K9ins15
c.26_27ins45
1 paper
NM_145185.4
p.L32L
c.96G>A
1 paper
NM_145185.4
p.S60fs
c.178_179fs
1 paper
NM_145185.4
p.H64L
c.191A>T
1 paper
NM_145185.4
p.T66P
c.196A>C
1 paper
NM_145185.4
p.P68delFs
c.204delC
1 paper
NM_145185.4
p.R72H
c.215G>A
1 paper
NM_145185.4
p.H73_L75delFs
c.219_225del7
1 paper
NM_145185.4
p.E88*
c.262G>T
1 paper
NM_145185.4
p.E88A
c.263A>C
1 paper
NM_145185.4
p.S89Splc
c.267-1G>A
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."