Varaico: Literature-Extracted Genetic Variants

Gene:MAP2K7
Variant:p.A147A

MAP2K7

110 papers

RefSeq Summary

The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically activates MAPK8/JNK1 and MAPK9/JNK2, and this kinase itself...

Pfam Domains

Pkinaseaa 120–380UCSCProtein kinase domain

Gene Aliases

HGNC Name

mitogen-activated protein kinase kinase 7

HGNC Previous Symbol

PRKMK7

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_145185.4
p.A147A
c.441C>T
Surrounding Variants
2 papers
NM_145185.4
p.R138C
c.412C>T
1 paper
NM_145185.4
p.M137T
c.410T>C
1 paper
NM_145185.4
p.G132S
c.394G>A
1 paper
NM_145185.4
p.G132delFs
c.394_395delGG
1 paper
NM_145185.4
p.G132_R138del7
c.394_413del21
1 paper
NM_145185.4
p.G129V
c.386G>T
1 paper
NM_145185.4
p.G129S
c.385G>A
2 papers
NM_145185.4
p.N118S
c.353A>G
1 paper
NM_145185.4
p.I117S
c.350T>G
1 paper
NM_145185.4
p.R152W
c.454C>T
2 papers
NM_145185.4
p.E116K
c.346G>A
1 paper
NM_145185.4
p.R153H
c.458G>A
UCSC Genome Browser·Imprint·Privacy·Terms·Feedback·Email Updates·

Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."