Varaico: Literature-Extracted Genetic Variants

Gene:MAP2K7
Variant:p.R162H

MAP2K7

110 papers

RefSeq Summary

The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically activates MAPK8/JNK1 and MAPK9/JNK2, and this kinase itself...

Pfam Domains

Pkinaseaa 120–380UCSCProtein kinase domain

Gene Aliases

HGNC Name

mitogen-activated protein kinase kinase 7

HGNC Previous Symbol

PRKMK7

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
3 papers
NM_145185.4
p.R162H
c.485G>A
Surrounding Variants
1 paper
NM_145185.4
p.R162C
c.484C>T
2 papers
NM_145185.4
p.D166E
c.498C>A
2 papers
NM_145185.4
p.D166E
c.498C>G
1 paper
NM_145185.4
p.S154F
c.461C>T
1 paper
NM_145185.4
p.R153H
c.458G>A
1 paper
NM_145185.4
p.R152W
c.454C>T
1 paper
NM_145185.4
p.C176Y
c.527G>A
1 paper
NM_145185.4
p.Y178C
c.533A>G
1 paper
NM_145185.4
p.N189N
c.567C>T
1 paper
NM_145185.4
p.A147A
c.441C>T
2 papers
NM_145185.4
p.R138C
c.412C>T
1 paper
NM_145185.4
p.M137T
c.410T>C
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."