Varaico: Literature-Extracted Genetic Variants

Gene:MAP2K7
Variant:p.E216K

MAP2K7

110 papers

RefSeq Summary

The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically activates MAPK8/JNK1 and MAPK9/JNK2, and this kinase itself...

Pfam Domains

Pkinaseaa 120–380UCSCProtein kinase domain

Gene Aliases

HGNC Name

mitogen-activated protein kinase kinase 7

HGNC Previous Symbol

PRKMK7

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_145185.4
p.E216K
c.646G>A
Surrounding Variants
1 paper
NM_145185.4
p.L219_A225del7
c.655_674del21
1 paper
NM_145185.4
p.K221ins15
c.662_663ins45
1 paper
NM_145185.4
p.M222V
c.664A>G
1 paper
NM_145185.4
p.V224E
c.671T>A
1 paper
NM_145185.4
p.T201I
c.602C>T
1 paper
NM_145185.4
p.M199L
c.595A>C
1 paper
NM_145185.4
p.M199L
c.595A>T
1 paper
NM_145185.4
p.M196I
c.588G>A
1 paper
NM_145185.4
p.M196I
c.588G>C
1 paper
NM_145185.4
p.M196I
c.588G>T
2 papers
NM_145185.4
p.A195T
c.583G>A
1 paper
NM_145185.4
p.D191D
c.573C>T
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."