Varaico: Literature-Extracted Genetic Variants

Gene:MAP2K7
Variant:p.S311_L312delFs

MAP2K7

110 papers

RefSeq Summary

The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically activates MAPK8/JNK1 and MAPK9/JNK2, and this kinase itself...

Pfam Domains

Pkinaseaa 120–380UCSCProtein kinase domain

Gene Aliases

HGNC Name

mitogen-activated protein kinase kinase 7

HGNC Previous Symbol

PRKMK7

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_145185.4
p.S311_L312delFs
c.931_935del5
Surrounding Variants
1 paper
NM_145185.4
p.V305L
c.913G>C
1 paper
NM_145185.4
p.V305L
c.913G>T
3 papers
NM_145185.4
p.D304N
c.910G>A
1 paper
NM_145185.4
p.R302Q
c.905G>A
2 papers
NM_145185.4
p.R302W
c.904C>T
1 paper
NM_145185.4
p.Y299C
c.896A>G
1 paper
NM_145185.4
p.D298D
c.894C>T
1 paper
NM_145185.4
p.P292T
c.874C>A
1 paper
NM_145185.4
p.D290insFs
c.869_870insC
2 papers
NM_145185.4
p.D290fs
c.868_869fs
1 paper
NM_145185.4
p.R288C
c.862C>T
1 paper
NM_145185.4
p.P286H
c.857C>A
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."